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Phenotypes Associated with This Genotype
Genotype
MGI:6452978
Allelic
Composition		 Setd3tm1.1(NCOM)Mfgc/Setd3tm1.1(NCOM)Mfgc
Genetic
Background		 involves: C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Setd3tm1.1(NCOM)Mfgc mutation (1 available); any Setd3 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to Riboviria infection ( J:293475 )
• no symptoms and severe reduction in viral load after intracerebral injection of CV-A10 or EV-A71 virus
• mild symptoms and barely detectable viral load after intramuscular injection of EV-D68 virus

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory