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Phenotypes Associated with This Genotype
Genotype
MGI:6452099
Allelic
Composition		 Pld4tm1.1Nemz/Pld4tm1.1Nemz
Tg(Itgax-cre)1-1Reiz/0
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pld4tm1.1Nemz mutation (0 available); any Pld4 mutation (29 available)
Tg(Itgax-cre)1-1Reiz mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal peritoneal macrophage morphology ( J:281205 )
• elevated expression of major histocompatibility complex (MHC) class II peptides on surface of resident peritoneal macrophages

immune system
abnormal peritoneal macrophage morphology ( J:281205 )
• elevated expression of major histocompatibility complex (MHC) class II peptides on surface of resident peritoneal macrophages

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory