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Phenotypes Associated with This Genotype
Genotype
MGI:6450215
Allelic
Composition		 Apoetm1(APOE_i4)Sfu/Apoetm1(APOE_i4)Sfu
Tg(APPSWE)2576Kha/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1(APOE_i4)Sfu mutation (4 available); any Apoe mutation (163 available)
Tg(APPSWE)2576Kha mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:121533 )
N
• amyloid beta deposits are scarcely seen at 15-16 months of age compared to the many in single Tg(APPSWE)2576Kha/0 mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory