Phenotypes for Cul3 Tg(GFAP-cre)25Mes MGI:6449669 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cul3^tm1Jdsr/Cul3^tm1Jdsr Tg(GFAP-cre)25Mes/0
Genetic Background	involves: 129S4/SvJaeSor * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cul3^tm1Jdsr mutation (1 available); any Cul3 mutation (51 available)
Tg(GFAP-cre)25Mes mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

decreased brain weight ( J:292173 )

absent corpus callosum ( J:292173 )

abnormal hippocampus morphology ( J:292173 )

• deformed hippocampus

abnormal stratification in cerebral cortex ( J:292173 )

thin cerebral cortex ( J:292173 )

mortality/aging

preweaning lethality ( J:292173 )

• mice die before age P17

growth/size/body

decreased body size ( J:292173 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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