Phenotypes Associated with This Genotype

Genotype
MGI:6437396

• Allelic Composition: Tesmin^em1Osb/Tesmin^em1Osb
• Genetic Background: involves: C57BL/6NJcl * DBA/2NJcl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

small testis ( J:288964 )

♂ • testes remain smaller throughout life

decreased testis weight ( J:288964 )

♂ • testicular weight is decreased in P14 mice but not P10 mice

arrest of spermatogenesis ( J:288964 )

♂ • spermatogenesis is predominately arrested at an early stage before the appearance of haploid spermatogenic cells

arrest of male meiosis ( J:288964 )

♂ • meiosis is arrested before late-pachytene stage

male infertility ( J:288964 )

♂

endocrine/exocrine glands

small testis ( J:288964 )

♂ • testes remain smaller throughout life

decreased testis weight ( J:288964 )

♂ • testicular weight is decreased in P14 mice but not P10 mice

cellular

arrest of male meiosis ( J:288964 )

♂ • meiosis is arrested before late-pachytene stage