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Phenotypes Associated with This Genotype
Genotype
MGI:6414954
Allelic
Composition		 Acvr1tm1Mak/Acvr1+
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Olig2tm1.1(cre)Wdr/Olig2+
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acvr1tm1Mak mutation (0 available); any Acvr1 mutation (43 available)
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze mutation (7 available); any Gt(ROSA)26Sor mutation (1098 available)
Olig2tm1.1(cre)Wdr mutation (1 available); any Olig2 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
increased oligodendrocyte number ( J:285841 )
• 2-fold increase in the number of oligodendroglial cells in the ventral brainstem at P7 and P21

cellular
increased oligodendrocyte number ( J:285841 )
• 2-fold increase in the number of oligodendroglial cells in the ventral brainstem at P7 and P21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory