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Phenotypes Associated with This Genotype
Genotype
MGI:6414948
Allelic
Composition		 Acvr1tm1.1Mak/Acvr1tm1.1Mak
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acvr1tm1.1Mak mutation (0 available); any Acvr1 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:285841 )
• mice die before or around birth

embryo
abnormal embryo development ( J:285841 )
• mutants exhibit developmental abnormalities

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory