Phenotypes Associated with This Genotype

Genotype
MGI:6408308

• Allelic Composition: Col1a2^{tm1b(EUCOMM)Wtsi}/Col1a2^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Col1a2^{tm1b(EUCOMM)Wtsi}/BayMmucd
• Cell Lines: EPD0536_7_E02

Data Sources

IMPC Data for Col1a2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - HAR

cardiovascular system

enlarged heart ( J:211773 )

♂

IMPC - HAR

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - HAR

enlarged spleen ( J:211773 )

♂

IMPC - HAR

hematopoietic system

enlarged spleen ( J:211773 )

♂

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

increased leukocyte cell number ( J:211773 )

♂

IMPC - HAR

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

increased large unstained cell number ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HAR

decreased circulating amylase level ( J:211773 )

IMPC - HAR

immune system

enlarged spleen ( J:211773 )

♂

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

increased leukocyte cell number ( J:211773 )

♂

IMPC - HAR

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

increased large unstained cell number ( J:211773 )

♂

IMPC - HAR

nervous system

abnormal optic disk morphology ( J:211773 )

♂

IMPC - HAR

vision/eye

abnormal optic disk morphology ( J:211773 )

♂

IMPC - HAR