Analysis Tools
nervous system
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• abducens nerve stalls and fails to innervate the lateral rectus and is absent from the orbit at E16.5
• oculomotor nerve aberrantly innervates the lateral rectus muscle, indicating compensatory innervation
• however, oculomotor nerve has a normal trajectory to the orbit
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• the number of abducens motor neurons is greatly reduced by E13.5, but is normal at E10.5, immediately prior to abducens stalling, indicating secondary motor neuron apoptosis by E13.5
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