Phenotypes Associated with This Genotype

Genotype
MGI:6404239

• Allelic Composition: Tg(Sftpc-cre)1Blh/0
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

respiratory system

abnormal lung morphology ( J:170336 )

• enlarged air spaces as early as E15.5

• dilated sacs at the periphery at P6 that may worsen with age

lung cyst ( J:170336 )

abnormal respiratory epithelium physiology ( J:170336 )

• increased apoptosis at E15.5

• 5-fold increase in apoptotic cells at E18.5

growth/size/body

lung cyst ( J:170336 )