Phenotypes Associated with This Genotype

Genotype
MGI:6403908

• Allelic Composition: Tg(Nes-cre/ERT2)4Imayo/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

increased miscarriage rate ( J:112466 )

• miscarrages in mice from dams treated with a high dose of tamoxifen beginning at E10.5

nervous system

decreased neuronal precursor proliferation ( J:112466 )

• at E19.5 in the subventricular zone of tamoxifen-treated mice

hydrocephaly ( J:112466 )

• in mice from dams treated with a high dose of tamoxifen beginning at E10.5

decreased brain size ( J:112466 )

• in mice from dams treated with a high dose of tamoxifen beginning at E10.5

cellular

decreased neuronal precursor proliferation ( J:112466 )

• at E19.5 in the subventricular zone of tamoxifen-treated mice