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Phenotypes Associated with This Genotype
Genotype
MGI:6402208
Allelic
Composition		 Tg(SFTPC-DPP4)3Pbmj/0
Genetic
Background		 involves: C57BL/6J * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(SFTPC-DPP4)3Pbmj mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal susceptibility to Coronaviridae infection ( J:285467 )
• mice can be infected with the EMC2012 strain of the Middle East respiratory-coronavirus (MERS-CoV) unlike wild-type mice, however they show no mortality or changes in body temperature although they fail to gain weight, and the virus is cleared by 14 days after infection

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory