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Phenotypes Associated with This Genotype
Genotype
MGI:6388638
Allelic
Composition		 Orc1tm1.1Gle/Orc1tm1.1Gle
Prl2c2tm1(cre)Gle/Prl2c2+
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Orc1tm1.1Gle mutation (0 available); any Orc1 mutation (60 available)
Prl2c2tm1(cre)Gle mutation (0 available); any Prl2c2 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:272584 )
• E10.5 embryos are viable and live mice are recovered at 3 weeks of age; placentae appear histologically normal and show no major alterations in trophoblast giant cell (TGC) endoreduplication, as determined by the nuclear size, genomic DNA content, BrdU incorporation and Ccna2 expression in E10.5 TGCs

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory