Analysis Tools
vision/eye
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• photoreceptors show a slow and progressive loss of 3 or 4 nuclear layers by P160
• however, photoreceptor development is normal
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• slow and progressive photoreceptor degeneration by P160
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• ERG shows that light-evoked response is progressively reduced in retinas by P160
• cones exhibit a greater functional loss than rods
• however, no changes in rod or cone responses are seen at P24
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• rod responses progressively decline with age, with maximal rod responses reduced by 82% at P160
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• cone responses are reduced by 92% at P160
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• progressive loss of vision
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nervous system
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• slow and progressive photoreceptor degeneration by P160
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