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Phenotypes Associated with This Genotype
Genotype
MGI:6367573
Allelic
Composition		 Gata6osem3Zfa/Gata6osem3Zfa
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Lgr5tm1(cre/ERT2)Cle/Lgr5+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata6osem3Zfa mutation (0 available); any Gata6os mutation (0 available)
Gt(ROSA)26Sortm1Sor mutation (10 available); any Gt(ROSA)26Sor mutation (1098 available)
Lgr5tm1(cre/ERT2)Cle mutation (1 available); any Lgr5 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal enterocyte proliferation ( J:268724 )
• reduced cycling and proliferation of intestinal stem cells
• however, proliferation rates are normal

digestive/alimentary system
abnormal enterocyte proliferation ( J:268724 )
• reduced cycling and proliferation of intestinal stem cells
• however, proliferation rates are normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory