About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6362876
Allelic
Composition
Tg(Myh6-Mtg1)3Ywxu/0
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• in response to pressure overload that is not as severe as in similarly treated wild-type mice
• in response to pressure overload that is not as severe as in similarly treated wild-type mice
• in response to pressure overload that is not as severe as in similarly treated wild-type mice
• in response to pressure overload that is not as severe as in similarly treated wild-type mice
• following pressure overload, mice exhibit reduced heart weight, cardiomyocyte cross-sectional area and cardiac fibrosis with improved contractile function compared with wild-type mice

respiratory system
• in response to pressure overload that is not as severe as in similarly treated wild-type mice

cellular
• reduction complex I, II and IV activity in response to pressure overload that is not as severe as in similarly treated wild-type mice

homeostasis/metabolism
• following pressure overload, mice exhibit reduced heart weight, cardiomyocyte cross-sectional area and cardiac fibrosis with improved contractile function compared with wild-type mice

muscle
• in response to pressure overload that is not as severe as in similarly treated wild-type mice
• in response to pressure overload that is not as severe as in similarly treated wild-type mice

growth/size/body
• in response to pressure overload that is not as severe as in similarly treated wild-type mice
• in response to pressure overload that is not as severe as in similarly treated wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory