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Phenotypes Associated with This Genotype
Genotype
MGI:6361694
Allelic
Composition		 Ppargtm2Rev/Ppargtm2Rev
Tg(Ucp1-cre)1Evdr/0
Genetic
Background		 involves: 129S4/SvJae * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppargtm2Rev mutation (1 available); any Pparg mutation (42 available)
Tg(Ucp1-cre)1Evdr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
adipose tissue
abnormal interscapular fat pad morphology ( J:278806 )
• composed of unilocular adipocytes and fibrotic tissues unlike in controls

homeostasis/metabolism
abnormal amino acid metabolism ( J:278806 )
• following cold exposure, mice fail to exhibit a decrease in branched-chains amino acid plasma concentration unlike in control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory