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Phenotypes Associated with This Genotype
Genotype
MGI:6361650
Allelic
Composition		 Mir216aem1Uf/Mir216aem1Uf
Genetic
Background		 C57BL/6-Mir216aem1Uf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir216aem1Uf mutation (0 available); any Mir216a mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
pancreatic acinar-to-ductal metaplasia ( J:278847 )
• in ductal cells cultured on collagen in the absence of growth factors
increased susceptibility to induced pancreatitis ( J:278847 )
• acute without complete regeneration leading to pancreatic ductal gland formation at day 4 following intraperitoneal injections of caerulein

immune system
increased susceptibility to induced pancreatitis ( J:278847 )
• acute without complete regeneration leading to pancreatic ductal gland formation at day 4 following intraperitoneal injections of caerulein

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory