Analysis Tools
normal phenotype
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• mice are viable, born in the expected Mendelian ratios, and overtly normal with no detectable defects in skeletal muscle development, as determined by fiber type distribution, number of satellite cells per muscle fiber, and fiber numbers and size in adult EDL and soleus muscles
• in vitro, satellite cell-derived myoblasts show no significant differences in proliferation or differentiation relative to wild-type cells
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