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Phenotypes Associated with This Genotype
Genotype
MGI:6361091
Allelic
Composition		 Chd9em2Ibbr/Chd9em2Ibbr
Genetic
Background		 C57BL/6N-Chd9em2Ibbr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd9em2Ibbr mutation (1 available); any Chd9 mutation (250 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:270181 )
N
• female homozygotes are fertile; when mated with male heterozygotes, females produce healthy pups with an average litter size of 6.2
abnormal oocyte morphology ( J:270181 )
• fluorescence recovery after photobleaching (FRAP) analysis using enhanced green fluorescent protein-tagged histone H2B (eGFP-H2B) revealed that mutant growing oocytes exhibit a lower recovery rate and a significantly lower mobile fraction (MF, an index of histone mobility) than wild-type oocytes, indicating a less loosened chromatin structure

cellular
abnormal oocyte morphology ( J:270181 )
• fluorescence recovery after photobleaching (FRAP) analysis using enhanced green fluorescent protein-tagged histone H2B (eGFP-H2B) revealed that mutant growing oocytes exhibit a lower recovery rate and a significantly lower mobile fraction (MF, an index of histone mobility) than wild-type oocytes, indicating a less loosened chromatin structure

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory