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Phenotypes Associated with This Genotype
Genotype
MGI:6360220
Allelic
Composition		 Nkx2-5em1Dsr/Nkx2-5em1Dsr
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nkx2-5em1Dsr mutation (0 available); any Nkx2-5 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
thin myocardium ( J:277399 )
• thin apical myocardial wall in embryos
abnormal heart ventricle morphology ( J:277399 )
• subtle abnormalities in the ventricular wall before the first week of life
abnormal trabecula carnea morphology ( J:277399 )
• mild hypertrabeculation and apical recesses in P3 ventricular wall

muscle
abnormal trabecula carnea morphology ( J:277399 )
• mild hypertrabeculation and apical recesses in P3 ventricular wall
thin myocardium ( J:277399 )
• thin apical myocardial wall in embryos

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory