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Phenotypes Associated with This Genotype
Genotype
MGI:6359479
Allelic
Composition		 Npc1tm2Tacf/Npc1tm2Tacf
Genetic
Background		 B6(Cg)-Npc1tm2Tacf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npc1tm2Tacf mutation (1 available); any Npc1 mutation (73 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:266795 )
• very low birth rate, with only 2% of homozygotes born

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory