Phenotypes Associated with This Genotype

Genotype
MGI:6357934

• Allelic Composition: Set^tm1.1Wgu/Set^tm1.1Wgu
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:276962 )

• all embryos die between E11.5 and E12.5

embryo

decreased embryo size ( J:276962 )

• at E9.5 and E10.5

• by E11.5 embryos are less than 20% the size of littermate controls

open neural tube ( J:276962 )

• at E10.5

homeostasis/metabolism

cardiac edema ( J:276962 )

• at E10.5

growth/size/body

decreased embryo size ( J:276962 )

• at E9.5 and E10.5

• by E11.5 embryos are less than 20% the size of littermate controls

nervous system

open neural tube ( J:276962 )

• at E10.5