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Phenotypes Associated with This Genotype
Genotype
MGI:6316684
Allelic
Composition
Syap1tm1a(EUCOMM)Hmgu/Y
Genetic
Background
Not Specified
Cell Lines HEPD0680_2_C02
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Syap1tm1a(EUCOMM)Hmgu mutation (1 available); any Syap1 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• normal voluntary running distance in a wheel
• normal preference for novel object in novel object recognition test
• normal fear conditioning
• normal preferences in dark-light transition test but with reduced overall locomotor activity
• normal preference for closed arms in elevated plus maze test
• very short latency to fall in accelerated and rocking rotation rotarod tests
• normal latency to fall with steady rotation in rotarod test
• slightly but significantly decreased grip strength in hind limbs
• reduction in total travel distance (mostly in periphery) within first 10 min. in open field test
• mostly stationary, showing orientation-like movement, in first 5 min. in open field test
• normal activity after 15-30 min. in open field test


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory