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Phenotypes Associated with This Genotype
Genotype
MGI:6314225
Allelic
Composition		 Atp1a2tm1.1Tmklh/Atp1a2tm1.1Tmklh
Genetic
Background		 involves: 129S1/Sv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp1a2tm1.1Tmklh mutation (0 available); any Atp1a2 mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:259556 )
• pups die immediately after birth

nervous system
abnormal hippocampus physiology ( J:259556 )
• glutamate uptake in hippocampus-derived in vitro embryo primary cultures is impaired

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory