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Phenotypes Associated with This Genotype
Genotype
MGI:6305148
Allelic
Composition		 PrkcbM5Btlr/PrkcbM5Btlr
Genetic
Background		 C57BL/6J-PrkcbM5Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
PrkcbM5Btlr mutation (0 available); any Prkcb mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgM level ( J:274861 )
• diminished T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)
impaired humoral immune response ( J:274861 )
• diminished T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

hematopoietic system
decreased IgM level ( J:274861 )
• diminished T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory