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Phenotypes Associated with This Genotype
Genotype
MGI:6285946
Allelic
Composition		 Mdm4m2Btlr/Mdm4m2Btlr
Genetic
Background		 C57BL/6J-Mdm4m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mdm4m2Btlr mutation (0 available); any Mdm4 mutation (191 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased CD4-positive, alpha-beta T cell number ( J:272830 )
• increased frequencies of CD4+ T cells in CD3+ T cells in the peripheral blood
decreased CD8-positive, alpha-beta T cell number ( J:272830 )
• reduced frequencies of CD8+ T cells and CD8+ T cells in CD3+ T cells in the peripheral blood

hematopoietic system
increased CD4-positive, alpha-beta T cell number ( J:272830 )
• increased frequencies of CD4+ T cells in CD3+ T cells in the peripheral blood
decreased CD8-positive, alpha-beta T cell number ( J:272830 )
• reduced frequencies of CD8+ T cells and CD8+ T cells in CD3+ T cells in the peripheral blood

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory