Phenotypes Associated with This Genotype

Genotype
MGI:6285913

• Allelic Composition: Macrod2^{tm1(KOMP)Vlcg}/Macrod2^{tm1(KOMP)Vlcg}
• Genetic Background: involves: C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:271238 )

• homozygotes are viable, healthy and overtly normal and show no significant changes in gamma-irradiation induced lethality, high fat diet-induced obesity, or response to glucose or insulin challenge relative to wild-type controls

• in response to gamma-irradiation, mouse embryonic fibroblasts (MEFs) isolated from E10.5 embryos exhibit DNA damage levels comparable to those observed in wild-type MEFs