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Phenotypes Associated with This Genotype
Genotype
MGI:6285655
Allelic
Composition
Chchd10em8Lutzy/Chchd10em8Lutzy
Genetic
Background
C57BL/6NJ-Chchd10em8Lutzy/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chchd10em8Lutzy mutation (1 available); any Chchd10 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• decline in forelimb grip strength is more severe in homozygotes than heterozygotes
• exercise intolerance is more severe in homozygotes than heterozygotes

growth/size/body
• body weight loss is more severe in homozygotes than heterozygotes

homeostasis/metabolism
• exercise intolerance is more severe in homozygotes than heterozygotes

mortality/aging
• shortened lifespan is more severe in homozygotes than heterozygotes


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory