About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6285543
Allelic
Composition		 Dock8M3Btlr/Dock8M3Btlr
Genetic
Background		 C57BL/6J-Dock8M3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock8M3Btlr mutation (0 available); any Dock8 mutation (101 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgG level ( J:272531 )
• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide
impaired humoral immune response ( J:272531 )
• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

hematopoietic system
decreased IgG level ( J:272531 )
• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory