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Phenotypes Associated with This Genotype
Genotype
MGI:6280331
Allelic
Composition		 Gt(ROSA)26Sortm1(DUX4)Sqh/Gt(ROSA)26Sor+
Tg(ACTA1-rtTA,tetO-cre)102Monk/0
Genetic
Background		 involves: 129S6/SvEvTac * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(DUX4)Sqh mutation (1 available); any Gt(ROSA)26Sor mutation (1062 available)
Tg(ACTA1-rtTA,tetO-cre)102Monk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased survivor rate ( J:268959 )
• less than 3% of the expected 25% of mutant pups are born and those pups then die immediately

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory