Phenotypes for Mpz Tg(Mpz)88.4Mfel MGI:6277901 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mpz^tm1Msch/Mpz⁺ Tg(Mpz)88.4Mfel/0
Genetic Background	FVB.Cg-Mpz^tm1Msch Tg(Mpz)88.4Mfel

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mpz^tm1Msch mutation (0 available); any Mpz mutation (28 available)
Tg(Mpz)88.4Mfel mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

decreased myelin sheath thickness ( J:77658 )

• myelin sheaths are thinner

• myelin lamellae are widened

• however, mice show improved hypomyelination

tomacula ( J:77658 )

• mice show tomacula that are not improved

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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