Phenotypes Associated with This Genotype

Genotype
MGI:6276352

• Allelic Composition: Ncoa6^tm1Jkr/Ncoa6⁺; Tg(Myh6-cre)2182Mds/0
• Genetic Background: involves: 129P2/OlaHsd * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

dilated cardiomyopathy ( J:269856 )

• mice exhibit characteristics of dilated cardiomyopathy with late onset

decreased cardiac muscle contractility ( J:269856 )

• decrease in percent fractional shortening

abnormal heart echocardiography feature ( J:269856 )

• echocardiography indicates decreased fractional shortening and enlarged left ventricular end-systolic dimensions and end-diastolic dimensions

muscle

dilated cardiomyopathy ( J:269856 )

• mice exhibit characteristics of dilated cardiomyopathy with late onset

decreased cardiac muscle contractility ( J:269856 )

• decrease in percent fractional shortening

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
dilated cardiomyopathy		DOID:12930	OMIM:PS115200	J:269856