Phenotypes Associated with This Genotype

Genotype
MGI:6272588

• Allelic Composition: Tg(Tyr-Ctnnb1/EGFP)#Lru/0
• Genetic Background: B6.Cg-Tg(Tyr-Ctnnb1/EGFP)#Lru

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal hair follicle melanogenesis ( J:176245 )

• at 7 days of age, mice show gray pigmentation in the hair follicle bulbs rather the dark pigmentation seen in wild-type controls

reduced hair shaft melanin granule number ( J:176245 )

• spectrophotometry revealed that hair melanin content is lower than that in wild-type controls

• however, melanin is distributed uniformly from the root to the apex as in wild-type hairs

abnormal pinna hair pigmentation ( J:176245 )

• mice exhibit gray ears, similar to their coat pigmentation

abnormal tail hair pigmentation ( J:176245 )

• mice exhibit gray tails, similar to their coat pigmentation

diluted coat color ( J:176245 )

• mice exhibit a gray coat, unlike the black coat color of wild-type controls

• transgenic hairs show a lighter pigmentation than wild-type hairs

integument

abnormal hair follicle melanogenesis ( J:176245 )

• at 7 days of age, mice show gray pigmentation in the hair follicle bulbs rather the dark pigmentation seen in wild-type controls

reduced hair shaft melanin granule number ( J:176245 )

• spectrophotometry revealed that hair melanin content is lower than that in wild-type controls

• however, melanin is distributed uniformly from the root to the apex as in wild-type hairs

abnormal pinna hair pigmentation ( J:176245 )

• mice exhibit gray ears, similar to their coat pigmentation

abnormal tail hair pigmentation ( J:176245 )

• mice exhibit gray tails, similar to their coat pigmentation

diluted coat color ( J:176245 )

• mice exhibit a gray coat, unlike the black coat color of wild-type controls

• transgenic hairs show a lighter pigmentation than wild-type hairs