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Phenotypes Associated with This Genotype
Genotype
MGI:6269169
Allelic
Composition		 Acsl6tm1Jeme/Acsl6tm1Jeme
Tg(Gfap-cre)77.6Mvs/0
Genetic
Background		 involves: BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acsl6tm1Jeme mutation (0 available); any Acsl6 mutation (46 available)
Tg(Gfap-cre)77.6Mvs mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased lipogenesis ( J:267563 )
• decreased omega-3 docosahexaenoic acid (DHA) levels in brain
• decreased omega-6 Arachidonate-containing phospholipids level in brain
• 57% decreased Acyl-CoA synthetase (ACS) in cerebellum

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory