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Phenotypes Associated with This Genotype
Genotype
MGI:6268704
Allelic
Composition		 Cr2M1Btlr/Cr2M1Btlr
Genetic
Background		 C57BL/6J-Cr2M1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cr2M1Btlr mutation (0 available); any Cr2 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgG level ( J:267527 )
• diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)
impaired humoral immune response ( J:267527 )
• diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

hematopoietic system
decreased IgG level ( J:267527 )
• diminished T-dependent antibody response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory