Phenotypes for Cd44 MGI:6268376 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cd44^M1Btlr/Cd44^M1Btlr
Genetic Background	C57BL/6J-Cd44^M1Btlr

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd44^M1Btlr mutation (0 available); any Cd44 mutation (67 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

decreased alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased CD4-positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased central memory CD4-positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased effector memory CD4-positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased CD8-positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased central memory CD8 positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

integument

alopecia ( J:267484 )

immune system

decreased alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased CD4-positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased central memory CD4-positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased effector memory CD4-positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased CD8-positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

decreased central memory CD8 positive, alpha-beta T cell number ( J:267483 )

• in the peripheral blood

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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