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Phenotypes Associated with This Genotype
Genotype
MGI:6257027
Allelic
Composition		 Bcl2tm1.1Sjk/Bcl2tm1.1Sjk
Tg(APPV717F)109Ili/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl2tm1.1Sjk mutation (1 available); any Bcl2 mutation (40 available)
Tg(APPV717F)109Ili mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:244104 )
• mice show a trend of exacerbated mortality compared to single Tg(APPV717F)109Ili expressing mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory