Phenotypes Associated with This Genotype

Genotype
MGI:6256971

• Allelic Composition: 5430431A17Rik^em1Doca/5430431A17Rik^em1Doca
• Genetic Background: C57BL/6-5430431A17Rik^em1Doca

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:266332 )

• mice do not survive more than a year compared to wild-type survival of 24 months to 38 months

cardiovascular system

increased heart weight ( J:266332 )

• relative to body weight

heart hyperplasia ( J:266332 )

• enlarged heart area

decreased heart left ventricle size ( J:266332 )

• decrease in ventricular chamber dimensions

decreased heart right ventricle size ( J:266332 )

• decrease in ventricular chamber dimensions

thick ventricular wall ( J:266332 )

• of the free walls

increased systemic arterial diastolic blood pressure ( J:266332 )

increased systemic arterial systolic blood pressure ( J:266332 )

muscle

abnormal skeletal muscle fiber morphology ( J:266332 )

• reduced cell area

growth/size/body

increased heart weight ( J:266332 )

• relative to body weight

heart hyperplasia ( J:266332 )

• enlarged heart area