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Phenotypes Associated with This Genotype
Genotype
MGI:6241556
Allelic
Composition		 Adam17tm1.2Bbl/Adam17tm1.2Bbl
Il23atm1Dnax/Il23atm1Dnax
Sox9tm3(cre)Crm/Sox9+
Genetic
Background		 involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adam17tm1.2Bbl mutation (1 available); any Adam17 mutation (62 available)
Il23atm1Dnax mutation (0 available); any Il23a mutation (21 available)
Sox9tm3(cre)Crm mutation (1 available); any Sox9 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
dermatitis ( J:229771 )
• mice develop eczematous dermatitis

integument
dermatitis ( J:229771 )
• mice develop eczematous dermatitis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory