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Phenotypes Associated with This Genotype
Genotype
MGI:6241441
Allelic
Composition		 Kif21atm1.1Ece/Kif21a+
Map1btm1Prop/Map1b+
Tg(Isl1-EGFP*)1Slp/0
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kif21atm1.1Ece mutation (0 available); any Kif21a mutation (80 available)
Map1btm1Prop mutation (0 available); any Map1b mutation (85 available)
Tg(Isl1-EGFP*)1Slp mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal abducens nerve morphology ( J:213171 )
• approximately 90% penetrance of abducens nerve hypoplasia
abnormal oculomotor nerve morphology ( J:213171 )
• oculomotor nerve superior branch axons terminate prematurely within a bulb with a penetrance of 90%

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory