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Phenotypes Associated with This Genotype
Genotype
MGI:6236324
Allelic
Composition
Tg(ACTB-EGFP,-Kcnj8*Q53R*G343D)1Nich/0
Tg(Myh11-icre/ERT2)1Soff/0
Genetic
Background
involves: C57BL/6 * CBA * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(ACTB-EGFP,-Kcnj8*Q53R*G343D)1Nich mutation (0 available)
Tg(Myh11-icre/ERT2)1Soff mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• systolic and diastolic blood pressures are lower 3 weeks following tamoxifen induction
• however, heart rate is not affected


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory