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Phenotypes Associated with This Genotype
Genotype
MGI:6220869
Allelic
Composition
Chek1tm1Jmr/Chek1+
Tg(Dct-lacZ)A12Jkn/0
Tg(Tyr-cre)1Lru/Y
Genetic
Background
involves: C57BL/6 * CBA * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chek1tm1Jmr mutation (1 available); any Chek1 mutation (41 available)
Tg(Dct-lacZ)A12Jkn mutation (5 available)
Tg(Tyr-cre)1Lru mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
N
• despite a slight reduction of melanoblast numbers at E13.5, adult mice exhibit normal coat pigmentation relative to control mice

embryo
• at E13.5, a slight but significant reduction of melanoblast numbers is noted in the head, dorsal, and ventral regions relative to control embryos

nervous system
• at E13.5, a slight but significant reduction of melanoblast numbers is noted in the head, dorsal, and ventral regions relative to control embryos


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory