Phenotypes Associated with This Genotype

Genotype
MGI:6209777

• Allelic Composition: Del(6Dlx6-Dlx5)1Tlu/+; Mef2c^tm1Eno/Mef2c⁺
• Genetic Background: involves: 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:122483 )

• all (9 of 9) double heterozygous mice are clearly cyanotic at birth and die on postnatal day 0 (P0)

craniofacial

abnormal palate development ( J:122483 )

• at P0, mice exhibit a small, misshapen, and incomplete palate

glossoptosis ( J:122483 )

• at P0, mice show an improper position of the tongue at the rear of the oral cavity

homeostasis/metabolism

cyanosis ( J:122483 )

• all mice are clearly cyanotic at birth

growth/size/body

abnormal palate development ( J:122483 )

• at P0, mice exhibit a small, misshapen, and incomplete palate

glossoptosis ( J:122483 )

• at P0, mice show an improper position of the tongue at the rear of the oral cavity

digestive/alimentary system

abnormal palate development ( J:122483 )

• at P0, mice exhibit a small, misshapen, and incomplete palate

glossoptosis ( J:122483 )

• at P0, mice show an improper position of the tongue at the rear of the oral cavity