Analysis Tools
pigmentation
belly spot
(
J:197025
)
|
• mice generally exhibit large white patches on the abdomen
|
integument
belly spot
(
J:197025
)
|
• mice generally exhibit large white patches on the abdomen
|
embryo
|
• fewer melanoblasts are observed on the forelimbs and trunks at E13.5 and E15.5, and significantly fewer melanoblasts are found in the distal areas
• however, the proportion of melanoblasts crossing into the epidermis at E13.5 is similar to that of wild-type controls
|
|
• fewer melanoblasts are observed in dorsal-ventral regions at E13.5 and E15.5
• however, the number and position of melanoblasts is normal at E11.5, suggesting no defects in neural crest cell to melanoblast differentiation or emigration from the neural tube
|
cellular
|
• fewer melanoblasts are observed on the forelimbs and trunks at E13.5 and E15.5, and significantly fewer melanoblasts are found in the distal areas
• however, the proportion of melanoblasts crossing into the epidermis at E13.5 is similar to that of wild-type controls
|
nervous system
|
• fewer melanoblasts are observed in dorsal-ventral regions at E13.5 and E15.5
• however, the number and position of melanoblasts is normal at E11.5, suggesting no defects in neural crest cell to melanoblast differentiation or emigration from the neural tube
|
