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Phenotypes Associated with This Genotype
Genotype
MGI:6199972
Allelic
Composition		 PnpM1Btlr/PnpM1Btlr
Genetic
Background		 C57BL/6J-PnpM1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
PnpM1Btlr mutation (0 available); any Pnp mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased IgM level ( J:265147 )
• diminished T-dependent antibody response to ovalbumin administered with aluminum hydroxide (OVA/alum)

immune system
increased IgM level ( J:265147 )
• diminished T-dependent antibody response to ovalbumin administered with aluminum hydroxide (OVA/alum)
impaired humoral immune response ( J:265147 )
• diminished T-dependent antibody response to ovalbumin administered with aluminum hydroxide (OVA/alum)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory