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Phenotypes Associated with This Genotype
Genotype
MGI:6199513
Allelic
Composition		 Plcg2M3Btlr/Plcg2M3Btlr
Genetic
Background		 C57BL/6J-Plcg2M3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plcg2M3Btlr mutation (0 available); any Plcg2 mutation (73 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B-1a cell number ( J:265101 )
• diminished T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

immune system
decreased B-1a cell number ( J:265101 )
• diminished T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)
abnormal humoral immune response ( J:265101 )
• diminished T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory