Phenotypes for Stat1 MGI:6199037 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Stat1^m4Btlr/Stat1^m4Btlr
Genetic Background	C57BL/6J-Stat1^m4Btlr

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat1^m4Btlr mutation (0 available); any Stat1 mutation (73 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased B cell number ( J:264800 )

decreased B-1 B cell number ( J:264800 )

decreased NK cell number ( J:264800 )

increased CD4-positive, alpha-beta T cell number ( J:264800 )

increased effector memory CD8-positive, alpha-beta T cell number ( J:264800 )

abnormal CD8-positive, naive alpha-beta T cell number ( J:264800 )

decreased CD8-positive, alpha-beta T cell number ( J:264800 )

increased NK T cell number ( J:264800 )

decreased single-positive T cell number ( J:264800 )

hematopoietic system

decreased B cell number ( J:264800 )

decreased B-1 B cell number ( J:264800 )

decreased NK cell number ( J:264800 )

increased CD4-positive, alpha-beta T cell number ( J:264800 )

increased effector memory CD8-positive, alpha-beta T cell number ( J:264800 )

abnormal CD8-positive, naive alpha-beta T cell number ( J:264800 )

decreased CD8-positive, alpha-beta T cell number ( J:264800 )

increased NK T cell number ( J:264800 )

decreased single-positive T cell number ( J:264800 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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