Phenotypes Associated with This Genotype

Genotype
MGI:6198744

• Allelic Composition: Vkorc1^tm1.1Kry/Vkorc1^tm1.1Kry; Tg(BGLAP-cre)1Clem/0
• Genetic Background: involves: FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:264734 )

N • slight but not significant improvement in glucose tolerance

abnormal circulating osteocalcin level ( J:264734 )

• decreased GLA-OCN, further upon prevention of coprophagy

• 10-fold increase in GLU-OCN levels

• however, total OCN levels are normal

hematopoietic system

hematopoietic system phenotype ( J:264734 )

N • unlike in null mice, no hemostatic defects were detected