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Phenotypes Associated with This Genotype
Genotype
MGI:6196216
Allelic
Composition
H2-D1tm1Bpe/H2-D1tm1Bpe
H2-K1tm1Bpe/H2-K1tm1Bpe
Klra1tm1.1Wyok/Klra1tm1.1Wyok
Genetic
Background
involves: 129P2/OlaHsd * BALB/cJ * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2-D1tm1Bpe mutation (9 available); any H2-D1 mutation (37 available)
H2-K1tm1Bpe mutation (9 available); any H2-K1 mutation (53 available)
Klra1tm1.1Wyok mutation (0 available); any Klra1 mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
N
• total number of NK cells, number of Ly49A+ NK cells, and their maturation profile as indicated by CD27 and CD11b expression
• NK cell licensing ratio (% Ifng+ Ly49+ versus Ifng+ Ly49- NK cells) lower than 1 as indicated by Ifng production after stimulation with anti-NK1.1


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory